The 1999–2000 Purdue Boilermakers men's basketball team represented Purdue University as a member of the Big Ten Conference during the 1999–2000 NCAA Division I men's basketball season. The team was led by Gene Keady and played its home games at Mackey Arena.

Roster

Schedule and results

!colspan=9 style=| Exhibition !colspan=9 style=| Regular season !colspan=9 style=| <span style=>Big Ten Tournament !colspan=9 style=| <span style=>NCAA tournament

NCAA basketball tournament

During the 2000 NCAA Division I men's basketball tournament, Purdue qualified for the Elite Eight, where they lost to the Wisconsin Badgers.

Rankings

Team players drafted into the NBA