The 2000 NCAA Division I men's basketball tournament involved 64 schools playing in single-elimination play to determine the national champion of men's NCAA Division I college basketball. It began on March 16, 2000, and ended with the championship game on April 3 in Indianapolis, Indiana at the RCA Dome. A total of 63 games were played. Due to a string of upsets throughout the tournament, only one top-four seed advanced to the Final Four. That was Michigan State, who finished the season as the #2 team in the nation and was given the top seed in the Midwest Region. The highest seeded of the other three Final Four teams was Florida, who won the East Region as the fifth seed. Two eight-seeds made the Final Four, with Wisconsin and North Carolina rounding the bracket out. Wisconsin won the West Region while North Carolina won the South Region, with both regions seeing their top three seeds eliminated during the first weekend of play. Michigan State won their first national championship since 1979 by defeating Florida 89–76 in the final game. Mateen Cleaves of Michigan State was named the tournament's Most Outstanding Player, while Morris Peterson was its leading scorer. Despite the string of upsets, no seed lower than 11 won a game in the tournament. The only 11 seed to win was Pepperdine, which defeated Indiana in the East Region's first round in what turned out to be Bob Knight's last game coaching the Hoosiers before his firing that offseason. Also, two teams that qualified as 10 seeds advanced to the Sweet Sixteen as Seton Hall in the East and Gonzaga in the West both advanced. Because of the upsets, the Elite Eight consisted of one top seed (Michigan State), one second seed (Iowa State), one third seed (Oklahoma State), one fifth seed (Florida), one sixth seed (Purdue), one seventh seed (Tulsa), and two eighth seeds (Wisconsin and North Carolina). This is the most recent title won by the Big Ten Conference.

Schedule and venues

The following are the sites that were selected to host each round of the 2000 tournament: First and Second Rounds Regional semifinals and finals (Sweet Sixteen and Elite Eight) National semifinals and championship (Final Four and championship)

Teams

There were 30 automatic bids awarded to the tournament - of these, 28 were given to the winners of their conference's tournament, while two were awarded to the team with the best regular-season record in their conference (Ivy League and Pac-10). Three conference champions made their first NCAA tournament appearances: UNC Wilmington (CAA), Central Connecticut State (NEC), and Southeast Missouri State (Ohio Valley). While the Mountain West Conference held a conference tournament, the conference was not granted an automatic bid to the tournament until the 2000–01 season.

Automatic qualifiers

Listed by region and seeding

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Bids by conference

Final Four

At RCA Dome, Indianapolis, Indiana

National semifinals

Championship game

Bracket

East Regional – Syracuse, New York

South Regional – Austin, Texas

# — Ohio State vacated 16 games including all NCAA Tournament wins from the 1999–00 season due to the Jim O’Brien scandal. Unlike forfeiture, a vacated game does not result in the other school being credited with a win, only with Ohio State removing the wins from its own record.

Midwest Regional – Auburn Hills, Michigan

West Regional – Albuquerque, New Mexico

Final Four at Indianapolis, Indiana

Broadcast information

Television

CBS Sports had exclusive TV coverage. They were carried on a regional basis until the "Elite Eight", at which point all games were shown nationally. Greg Gumbel once again served as the studio host, joined by analyst Clark Kellogg.

Radio

Westwood One had exclusive radio coverage. Tommy Tighe once again served as studio host.

Local radio