The Journal of Nervous and Mental Disease is a peer-reviewed medical journal on psychopathology. It was established in 1874 as the Chicago Journal of Nervous and Mental Disease. "Chicago" was dropped from the title beginning in 1876. Articles cover theory, etiology, therapy, and social impact of illness, and research methods.

Editors-in-chief

The following people have been editors-in-chief of this journal: • 1874–1881: James Stewart Jewell • 1882–1885: W. J. Morton • 1886–1887: Bernard Sachs • 1888–1889: C. H. Brown • 1889–1890: G. M. Hammond • 1890–1901: C. H. Brown • 1902–1944: Smith Ely Jelliffe • 1945–1957: N. D. C. Lewis • 1958–1959: J. E. Finesinger • 1961–1967: L. S. Kubie • 1967–2010: E.B. Brody • 2010–present: John A. Talbott