The Sykesville Historic District encompasses the center of Sykesville, Maryland. Sykesville is a small incorporated town in the Patapsco River valley in southern Carroll County, Maryland, and is located on the old main line of the Baltimore and Ohio Railroad (B&O), one of the first railroad lines in the United States, that section dating from 1831. The B&O train station is included in the district, next to the river. It was designed by E. Francis Baldwin in the Queen Anne style and built in 1883. It is currently a restaurant having outdoor seating on the original platform (only goods trains now pass). Other historically significant buildings in the district were built between the 1850s and the 1920s.