St. Paul University Manila (SPUM), also referred by its acronym SPU Manila, is a private, Catholic coeducational basic and higher education institution established and run by the Congregation of the Sisters of Saint Paul of Chartres in Manila, Philippines. It was established in 1912 by the Sisters of St. Paul of Chartres (SPC), a religious congregation founded in Chartres, France in 1698. It was previously an all-girls' school and turned co-ed beginning school year 2005-2006. In 1912, St. Paul Manila opened a Kindergarten school with an enrollment of six girls, upon request of the families in the neighborhood.The school was named St. Paul Institution. Grade I was opened in 1913 with one higher grade opened each year and boys accepted up to Grade 2. The Grade School Department was given government recognition when it has reached Grade 6. It is one of the 40 schools owned, managed, and operated by the Sisters of St. Paul of Chartres (SPC) in the Philippines. It is one of the seven campuses comprising the St. Paul University System.

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