St. Paul's Episcopal Church and Cemetery is a historic church on Cowles Street between Woodland Boulevard and West Street in Wilkesboro, North Carolina. It was added to the National Register of Historic Places in 1982 as a Historic Place in Wilkes County, North Carolina. St. Paul's was built in 1848 and is the most important example of the Gothic Revival style in Wilkesboro as well as being a typical example of many American Episcopal churches built during the mid nineteenth century. A small brick structure, the church incorporates many Gothic features which bear similarity with those of English medieval parish churches; these include a steep gable roof, corner buttresses, lancet arched windows and doors, and plentiful Gothic interior detailing.