Sioux Lookout railway station is located in the town of Sioux Lookout, Kenora District in northwestern Ontario, Canada. The station is on the Canadian National Railway transcontinental main line; it is used by Via Rail and served by transcontinental Canadian trains. The station was opened in 1911 and remodelled in 1937; it was listed on the Canadian Register in 2008. Via Rail uses a heated shack near the historic station building.