A sialogogue (also spelled sialagogue, ptysmagogue or ptyalagogue) is a substance, especially a medication, that increases the flow rate of saliva. The definition focuses on substances that promote production or secretion of saliva (proximal causation) rather than any food that is mouthwatering (distal causation that triggers proximal causation). Sialogogues can be used in the treatment of xerostomia (the subjective feeling of having a dry mouth), to stimulate any functioning salivary gland tissue to produce more saliva. Saliva has a bactericidal effect, so when low levels of it are secreted, the risk of caries increases. Not only this, but fungal infections such as oral candidosis also can be a consequence of low salivary flow rates. The buffer effect of saliva is also important, neutralising acids that cause tooth enamel demineralisation.

Usage in dentistry

The following are used in dentistry to treat xerostomia:

Historical source from plants

A tincture is prepared from the root of the pyrethrium (pyrethrum) or pellitory (a number of plants in the Chrysanthemum family). It is found growing in Levant and parts of Limerick and Clare in Ireland. The root powder was used as flavouring in tooth powders in the past.

Herbs with sialogogue action