**Serum **total protein****, also known as total protein, is a clinical chemistry parameter representing the concentration of protein in serum. Serum contains many proteins including serum albumin, a variety of globulins, and many others. While it is possible to analyze these proteins individually, total protein is a relatively quick and inexpensive analysis that does not discriminate by protein type. The traditional method for measuring total protein uses the biuret reagent, but other chemical methods such as dye-binding and refractometry are now available. The measurement is usually performed on automated analysers along with other laboratory tests.

Interpretation

The reference range for total protein is typically 60-80g/L. (It is also sometimes reported as "6.0-8.0g/dl"), but this may vary depending on the method of analysis.