The Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Comedy Series is an award given by the Screen Actors Guild to honor the finest female acting achievement in a comedy series. Actresses are eligible for the award whether they appear in leading or supporting roles in their respective programs. Julia Louis-Dreyfus holds the record for both the most wins (5) and nominations (12). She won twice for playing Elaine Benes in Seinfeld (1996, 1997) and thrice for playing Selina Meyer in Veep (2013, 2016, 2017). Tina Fey has earned four wins for her role as Liz Lemon in 30 Rock. Actresses who received seven nominations include Edie Falco, Tina Fey and Megan Mullally.

Winners and nominees

1990s

2000s

2010s

2020s

Superlatives

Trivia

Multiple winners

Multiple nominees