Schiller–Duval body

1

Schiller–Duval body is a cellular structure seen by microscope in endodermal sinus tumors (yolk sac tumors) which are the most common testicular cancer in children. Schiller-Duval bodies are present in approximately 50% of these tumors, and if found are pathognomonic. They are named for Mathias-Marie Duval and Walter Schiller who described them in the late nineteenth century. Schiller–Duval bodies are said to resemble a glomerulus. They have a mesodermal core with a central capillary, all lined by flattened layers of both visceral and parietal cells. Immunofluorescent stain may show eosinophilic hyalin-like globules both inside and outside the cytoplasm that contain AFP and alpha 1-antitrypsin.

This article is derived from Wikipedia and licensed under CC BY-SA 4.0. View the original article.

Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.
Bliptext is not affiliated with or endorsed by Wikipedia or the Wikimedia Foundation.

Edit article