Sant'Antonio di Gallura (Gallurese: Sant' Antòni, ) is a municipality in the Province of Sassari in the Italian region Sardinia, located about 200 km north of Cagliari and about 20 km northwest of Olbia. Sant'Antonio di Gallura borders the following municipalities: Arzachena, Calangianus, Luras, Olbia, Telti. The economy is based on agriculture, animal husbandry and production of cork. People move seasonally to the nearby Arzachena and Olbia to work in touristic structures.