The Roman Catholic Diocese of León in Nicaragua (erected 3 November 1534) is a suffragan of the Archdiocese of Managua.

Bishops

• Diego Álvarez de Osorio (1531–1536 Died) • Francisco de Mendavia (1537–1540 Died) • Antonio de Valdivieso (1544–1549 Died) • ::Vicar Capitular, Father Martin Hernández de Herrera (1550–1555) • Fernando González de Bariodero (1555– ) • ::Vicar Capitular, Father Juan Alvarez (1555–1557) • Lázaro Carrasco (1557–1562 Died) • Luís de la Fuente (bishop) (1564–1566 Died) • Pedro Gómez de Córdoba (1568–1574 Appointed, Bishop of Santiago de Guatemala) • Antonio de Zayas (bishop) (1575–1582 Resigned) • Domingo de Ulloa (1585–1591 Appointed, Bishop of Popayán) • Jerónimo de Escobar (1592–1593 Died) • Alfonso de la Mota y Escobar (1594–1595 Resigned as Bishop Elect) • Juan Antonio Diaz de Salcedo (1597–1603 Died) • Pedro de Villarreal (1603–1619 Died) • Benito Rodríguez Valtodano (1621–1629 Died) • Agustin de Hinojosa y Montalvo (1630–1631 Died) • Juan Barahona Zapata del Águila (1632–1632 Died) • Fernando Núñez Sagredo (1633–1639 Died) • Miguel de Poblete Casasola (1640 Resigned and later appointed Archbishop of Manila) • Alonso de Briceño (Brizeño) (1644–1653 Appointed, Bishop of Caracas, Santiago de Venezuela) • Tomás Manso (1658–1659 Died) • Juan de la Torre y Castro (1661–1662 Died) • Alfonso Bravo de Laguna (1670–1674 Died) Vicar Capitular from 1660 • Andrés de las Navas y Quevedo (1677–1683 Confirmed, Bishop of Santiago de Guatemala) • Juan de Rojas y Asúa (1683–1685 Died) • Nicolás Delgado (1687–1698 Died) • Diego Morcillo Rubio de Suñón de Robledo (1701–1708 Appointed, Bishop of La Paz) • Juan Benito Garret y Arlovi (1708–1716 Died) • Andrés Quiles Galindo (1718–1719 Died) • José Xirón de Alvarado (1721–1724 Died) • Francisco Dionisio de Villavicencio (1726–1735 Died) • Domingo Antonio de Zatarain (1738–1741 Died) • Isidoro Marín Bullón y Figueroa (1743–1748 Died) • Pedro Agustín Morell de Santa Cruz y Lora (1749–1753 Confirmed, Bishop of Santiago de Cuba) • José Antonio Flores de Rivera (1753–1756 Died) • Matías José de Navia Bolaños y Moscoso (1757–1762 Died) • Juan Carlos de Vilches y Cabrera (1765–1774 Died) • Esteban Lorenzo de Tristán y Esmenota (1775–1783 Appointed, Bishop of Durango) • Juan Félix de Villegas (1785–1793 Appointed, Archbishop of Guatemala) • Juan Cruz Ruiz de Cabañas y Crespo (1794–1795 Appointed, Bishop of Guadalajara) • José Antonio de la Huerta Caso (1797–1803 Died) • Felipe Antonio (Juan José) Pérez del Notario (1804–1806 Died) • Nicolás García Jerez (1806–1825 Died) • Jorge de Viteri y Ungo (1849–1853 Died) • José Bernardo Piñol y Aycinena (1854–1867 Appointed, Archbishop of Guatemala) • Manuel Ulloa y Calvo (1867–1879 Died) • Francisco Ulloa y Larios (1880–1896 Retired) • Simeón Pereira y Castellón (1902–1921 Died)

Coadjutor bishops

Auxiliary bishop

Other priests of this diocese who became bishops

Territorial losses

Metropolitans

Since it was erected, the see has had four metropolitans.