Route 344 is an east/west highway on the north shore of the Ottawa River in Quebec, Canada. Its western terminus is in Grenville-sur-la-Rouge at the junction of Autoroute 50, and its eastern terminus is in L'Assomption at the junction of Route 343. It follows the Ottawa River from Grenville-sur-la-Rouge to Saint-André-d'Argenteuil, where it follows the Lac des Deux Montagnes until Deux-Montagnes, where it follows the Rivière des Mille Îles until Repentigny, where it follows the Rivière l'Assomption until L'Assomption.

Municipalities along Route 344