Prince of Sulmona (Italian: Principe di Sulmona) is a noble title of Italian origin. The title derives its name from Sulmona, a town in Abruzzo. It was originally granted in 1526 with Grandeeship of Spain, during the reign of Charles V, Holy Roman Emperor as King of Naples, in recognition of the work done by Charles de Lannoy as Viceroy of Naples. That line of princes died out in 1604. The title was recreated in 1610 for Pope Paul V's nephew Marcantonio Borghese by King Philip III of Spain, in his capacity as king of Naples (just like in England, prince titles were alien to the Spanish peerage tradition). King Philip III sold the principality and the town of Sulmona to the Borghese Family, and the title still remains in this family. After the unification of Italy, the title was recognized by the new Kingdom of Italy.

House of Lannoy, 1526–1604

House of Borghese, 1610–present