This is a list of winners and nominees of the Primetime Emmy Award for Outstanding Supporting Actor in a Comedy Series. In early Primetime Emmy Award ceremonies, the supporting categories were not always genre, or even gender, specific. Beginning with the 22nd Primetime Emmy Awards, supporting actors in comedy have competed alone. However, these comedic performances often included actors from miniseries, telefilms, and guest performers competing against main cast competitors. Such instances are marked below:

Winners and nominations

1950s

1960s

1970s

1980s

1990s

2000s

2010s

2020s

Superlatives

Programs with multiple wins

Programs with multiple nominations

Performers with multiple wins

Performers with multiple nominations