The Primetime Emmy Award for Outstanding Lead Actor in a Drama Series is an award presented by the Academy of Television Arts & Sciences (ATAS). Beginning with the 18th Primetime Emmy Awards, leading actors in drama have competed alone. However, these dramatic performances included actors from miniseries, telefilms, and guest performers competing against main cast competitors. Such instances are marked below:

Winners and nominations

1950s

1960s

1970s

1980s

1990s

2000s

2010s

2020s

Programs with multiple wins

Programs with multiple nominations

Performers with multiple wins

Performers with multiple nominations

(*) refers to those who have won in this category

Superlatives