ppc64 is an identifier commonly used within the GNU/Linux, GNU Compiler Collection (GCC) and LLVM free software communities to refer to the target architecture for applications optimized for 64-bit big-endian PowerPC and Power ISA processors. ppc64le is a pure little-endian mode that has been introduced with the POWER8 as the prime target for technologies provided by the OpenPOWER Foundation, aiming at enabling porting of the x86 Linux-based software with minimal effort.

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These two identifiers are frequently used when compiling source code to identify the target architecture. 64-bit Power and PowerPC processors are the following: Defunct 64-bit PowerPC processors are the Motorola G5 and PowerPC e700.