Contents
Potassium canrenoate
Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), also known as aldadiene kalium, the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group. Like spironolactone, it is a prodrug, and is metabolized to active canrenone in the body. Potassium canrenoate is notable in that it is the only clinically used antimineralocorticoid which is available for parenteral administration (specifically intravenous) as opposed to oral administration. In the UK, it is unlicensed and only used for short term diuresis in oedema or heart failure in neonates or children under specialist initiation and monitoring.
This article is derived from Wikipedia and licensed under CC BY-SA 4.0. View the original article.
Wikipedia® is a registered trademark of the
Wikimedia Foundation, Inc.
Bliptext is not
affiliated with or endorsed by Wikipedia or the
Wikimedia Foundation.