The Pence Springs Hotel Historic District is a national historic district located at Pence Springs, Summers County, West Virginia. It encompasses seven contributing buildings and two contributing structures. They are the Pence Springs Hotel Building (1916-1918), Pavilion / Casino (1919), Hotel Manager's Residence / Warden's Residence (c. 1919), Hotel Garage (1925), Golf Caddy House (1919), Pence Springs Bottling Works (c. 1915), and Pence Springhouse (c. 1901). It was listed on the National Register of Historic Places in 1985.