Peligrotherium is an extinct meridiolestidan mammal from the Paleocene of Patagonia, originally interpreted as a stem-ungulate (though it did co-exist with early meridiungulates). Its remains have been found in the Salamanca Formation. It was a dog-sized mammal, among the largest of all non-therian mammals (as well as the largest South American Paleocene mammal ). It is a member of Mesungulatoidea, a clade of herbivorous meridiolestidans with molars that had rounded (bunodont) cusps.

Diet

A biomechanical study finds Peligrotherium to be a herbivore functionally similar to the black rhino.