The Pawtuckaway River is a 3.6 mi river in southeastern New Hampshire in the United States. It is a tributary of the Lamprey River, part of the Great Bay and Piscataqua River watershed leading to the Atlantic Ocean. The river forms the south outlet of Pawtuckaway Lake, a 900 acre lake in the town of Nottingham, New Hampshire. The river travels southeast through a wooded valley, passing under New Hampshire Route 156, entering the town of Raymond briefly, then crossing into Epping, where it joins the Lamprey River near the village of West Epping.