The National Planning Commission of South Africa is a South African government agency established in May 2010, responsible for strategic planning for the country. The head of the commission reports to the President, and works with various ministries to co-ordinate joint priority projects that require a multifaceted approach. Trevor Manuel was appointed the first head of the commission by President Jacob Zuma. The commission is chaired by the Minister in the Presidency, heading a panel of "external experts". To avoid turf wars, it will not include Ministers. In June 2014, then Deputy President, Cyril Ramaphosa, was appointed as the Chairman of the Commission with Minister in the Presidency Jeff Radebe as his deputy. In December 2021, a third National Planning Commission for the period 2021-2026 was established, with Minister in the Presidency, Mondli Gungubele, appointed as Chairperson.

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