Monocytopenia is a form of leukopenia associated with a deficiency of monocytes. It has been proposed as a measure during chemotherapy to predict neutropenia, though some research indicates that it is less effective than lymphopenia.

Causes

The causes of monocytopenia include: acute infections, stress, treatment with glucocorticoids, aplastic anemia, hairy cell leukemia, acute myeloid leukemia, treatment with myelotoxic drugs, intestinal resection, and genetic syndromes, as for example MonoMAC syndrome.

Diagnosis

• Blood Test (CBC) (Normal range of Monocytes: 1-10%) (Normal range in males: 0.2-0.8 x 10 3 /microliter)
• Blood test checking for monocytopenia (Abnormal ranges: <1%) (Abnormal range in males: <0.2 x 10 3 /microliter)

Treatment

Monocytopenia may be treated with hematopoietic stem cell transplantation.