Route 210 is a highway in western Missouri with an eastern terminus at Route 10 southwest of Richmond and a western terminus at Interstate 29, 35, and U.S. Route 71. After I-29 and 35, 210 immediately intersects Route 1 and continues east. It intersects Walker Road in front of NKC Hospital and the Cerner world headquarters before an interchange with Chouteau Trafficway near North Kansas City, Missouri. It becomes a limited access freeway as it exits North Kansas City and into Kansas City proper. There are interchanges with North Brighton Avenue and Northeast Searcy Creek Parkway before it intersects I-435. Here, it reverts to a four-lane road with stoplights. It has intersections with the frontage road, Great Midwest Drive, and Eldon Road before becoming a two-lane road and going onto the river bottoms. It goes straight east, intersecting several roads, before curving northeast to intersect with Route 291.

Major intersections