The minister of foreign affairs is the head of the Ministry of Foreign Affairs and a member of the Cabinet and the Council of Ministers. The incumbent minister is Caspar Veldkamp of the New Social Contract (NSC) party, who has been in office since 2 July 2024. Regularly, a state secretary is assigned to the ministry who is tasked with specific portfolios, currently the function is not in use. Additionally since 1965 there has been a minister without portfolio assigned to the ministry, the minister for foreign trade and development cooperation has traditionally development cooperation as portfolio, since 2012 the portfolio of trade and export has been assigned added to the function.

List of agents of foreign affairs (1798–1801)

List of secretaries of state of foreign affairs (1801–1806)

List of ministers of foreign affairs

1806–1868

1868–1918

Since 1918

List of ministers without portfolio

List of state secretaries for foreign affairs (since 1950)