The Minister of Defence of the Soviet Union refers to the head of the Ministry of Defence who was responsible for defence of the socialist/communist Russian Soviet Federative Socialist Republic from 1917 to 1922 and the Soviet Union from 1922 to 1992.

People's Commissars for Military and Naval Affairs (1917–1934)

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People's Commissars for Defence (1934–1946)

People's Commissars for the Navy (1937–1946)

People's Commissar for the Armed Forces (1946)

Ministers of the Armed Forces (1946–1950)

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Minister of War (1950–1953)

Ministers of the Navy (1950–1953)

Ministers of Defence (1953–1992)