Several counties in the state of Michigan use a Mile Road System to name different roads and streets. The most commonly known system is that of Detroit, including 8 Mile Road, the dividing line between Detroit and its northern suburbs as well as Wayne County and Oakland, Macomb and Washtenaw counties. The roads in the Detroit-area system are laid out in a grid and named with reference to a zero-mile "point of origin" in Campus Martius Park in downtown Detroit.

Bay County

In Bay County, roads west of the Saginaw River are numbered with the river (or, north of the river, State Street) marking the origin.

Calhoun County

Going east from the county line between Calhoun and Kalamazoo counties. Many of the roads are known by both their mile names and their traditional names.

Metropolitan Detroit

Grand Traverse County

In Grand Traverse County, the mile roads are numbered from the location of the Boardman River and the ghost town of Keystone, named after its location at an important point on the river.

Kent County

Fulton Street is the north–south dividing line of the city of Grand Rapids. But since Fulton Street is on a half-section line, Michigan Street is the baseline in Kent County, not Fulton Street.

Manistee County

In Manistee County, roads are numbered north from the village of Eastlake

Midland County