Michele Tenore (5 May 1780 – 19 July 1861) was an Italian botanist active in Naples, Italy. Tenore studied at the University of Naples, receiving his medical degree in 1800. Tenore was a friend of botanists Domenico Maria Leone Cirillo (1739–1799) and Vincenzo Petagna (1734–1810). Tenore made numerous botanical excursions into Abruzzo and particularly Majella, and gave private courses in botany. In 1811, he succeeded Petagna to the university's chair in botany. Tenore helped establish the Botanical Garden of Naples, and became its director in 1810. He also served as president of the Accademia nazionale delle scienze, and served as president of the Accademia Pontaniana six times from the 1830s through the 1850s. In 1853, Tenore founded the Tenore prize, a prize still awarded from the Accademia Pontaniana.

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