Mexico High School is a historic school building located in Mexico, Oswego County, New York. It is part of the Mexico Central School District. It was built in 1938 after a previous 1927 building was damaged by fire in 1937. It is a two-story, Georgian Revival style brick building in a U-shaped plan. It features a distinctive tower that contains an 1828 bell from an earlier building. The entry is distinguished by a two-story, five-bay portico supported by six Ionic columns and crowned by a Chippendale patterned balustrade. It was listed on the National Register of Historic Places as the Mexico Academy and Central School in 1991.