Melincué is a town (comuna) in the south of the, 287 km from the provincial capital. It has about 2,200 inhabitants as per the and it is the head town of the General López Department. It was founded in 1872 and recognized officially as a town on 3 September 1986. Melincué is located immediately north of an endorheic lake (Laguna Melincué) and an associated wetland area that is included in a nature reserve. The fluctuating level of the Melincué Lake and the lack of hydrical infrastructure have often caused the town to suffer floods.