Matrice is a comune (municipality) in the Province of Campobasso in the Italian region Molise, located about 7 km northeast of Campobasso. As of 31 December 2004, it had a population of 1,081 and an area of 20.4 km2. Matrice borders the following municipalities: Campobasso, Campolieto, Castellino del Biferno, Montagano, Petrella Tifernina, Ripalimosani, San Giovanni in Galdo. At the beginning of the 20th century, many residents of Matrice began to immigrate to the U.S.

Demographic evolution