Mark Grigorievich Krein (, ; 3 April 1907 – 17 October 1989) was a Soviet mathematician, one of the major figures of the Soviet school of functional analysis. He is known for works in operator theory (in close connection with concrete problems coming from mathematical physics), the problem of moments, classical analysis and representation theory. He was born in Kyiv, leaving home at age 17 to go to Odesa. He had a difficult academic career, not completing his first degree and constantly being troubled by anti-Semitic discrimination. His supervisor was Nikolai Chebotaryov. He was awarded the Wolf Prize in Mathematics in 1982 (jointly with Hassler Whitney), but was not allowed to attend the ceremony. David Milman, Mark Naimark, Israel Gohberg, Vadym Adamyan, Mikhail Livsic and other known mathematicians were his students. He died in Odesa. On 14 January 2008, the memorial plaque of Mark Krein was unveiled on the main administration building of I.I. Mechnikov Odesa National University.