The Lytton First Nation, a First Nations band government, has its headquarters at Lytton in the Fraser Canyon region of the Canadian province of British Columbia. While it is the largest of all Nlaka'pamux bands, unlike all other governments of the Nlaka'pamux (Thompson) people, it is not a member of any of the three Nlaka'pamux tribal councils, which are the Nicola Tribal Association, the Fraser Canyon Indian Administration and the Nlaka'pamux Nation Tribal Council. The Lytton First Nation figure prominently in the history of the Fraser Canyon Gold Rush (1858-1860) and of the associated Fraser Canyon War (1858). At Lytton, then still called Kumsheen, leaders of the miners' regiments from Yale met with the chiefs of the Nlaka'pamux to parley an end to the war. While other chiefs argued for annihilation of the outsiders, the Kumsheen chief Spintlum (Cxpentlm, aka David Spintlum) argued for peace, resulting in a series of six treaties known as the Snyder Treaties, which are lost to history.

Indian reserves

Indian reserves under the governance of the Lytton First Nation are: