Luis Ernesto Sharpe (born June 16, 1960) is a former professional American football tackle who played 13 seasons in the National Football League (NFL) for the St. Louis/Phoenix/Arizona Cardinals from 1982 through 1994. A 3-time Pro Bowl selection, Sharpe was selected by the Cardinals in the 1st round (16th overall) of the 1982 NFL draft. He also played for the Memphis Showboats of the USFL in 1985. Sharpe graduated from UCLA with a degree in political science.