The Central Region was a region that competed in the Little League World Series between and. It was inaugurated as the North Region in, when the LLWS first gave out Series berths to regional winners. The region was renamed to Central in, and in was split into the Midwest and Great Lakes regions. The region produced one world champion, in, when Hamtramck, Michigan, defeated Auburn, California, 12–0, in the championship game. The region consisted of teams from the Dakotas, Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, Oklahoma, Ohio, and Wisconsin. In 2000, Kentucky replaced Oklahoma in the region. Little League Baseball expanded the LLWS to sixteen teams for the 2001 Little League World Series. The Central Region was split into the Midwest Region (the Dakotas, Iowa, Kansas, Minnesota, Missouri, and Nebraska) and the Great Lakes Region (Illinois, Indiana, Kentucky, Michigan, Ohio, and Wisconsin).

Regional Champions (1957–2000)

The following table indicates the Central Region champion and its LLWS performance in each year between 1957 and 2000.

Results by State