This list ranks buildings in the U.S. city of Syracuse, New York, by height. Since its construction in 1927, the State Tower Building has been the tallest building in Syracuse. Bricks on the facade of the State Tower Building gradually get lighter towards the top of the Art Deco building; this was intended to make the building seem higher than it actually is. The building is listed on the National Register of Historic Places as a contributing property in the Hanover Square Historic District. It was renovated in 2003 and 2016. St. Paul's Episcopal Cathedral, one of the top 10, was constructed in the 1800s. Eight tall buildings were constructed in the 1970s, and apparently demand for office space has not required new buildings since.

Cancelled buildings

Proposed construction of the "Primex Building" never got past foundation work being done, in a project planned to be completed in 1964. It was to have a revolving restaurant, and, at 25 stories, would have been the tallest building in New York State outside of New York City. On October 24, 2002, the groundbreaking for a 430 ft, 47-story Destiny USA Hotel to be named the Grand Destiny Hotel was held. On that date a steel beam was driven into the Carousel Center parking lot. Over the next three weeks, over 40 more pilings were driven, but by December 2 construction had stopped. In July 2008 construction had restarted, and by August three stories of steel framework had been erected. OnCenter Convention Center Marriott Hotel was a planned 12- or 16-floor building, 58.28 m] in 2004 and eventually cancelled. In 2001 Clinton Square North Tower was a planned 16-floor, 74.49 m complex built alongside Chase Tower and eventually cancelled.