The U.S. city of San Antonio, Texas is home to 93 high-rises, 15 of which are skyscrapers that stand at least 328 ft feet tall. The tallest structure in the city, excluding radio antennas, is the Tower of the Americas, standing 750 ft tall. Completed for HemisFair '68, it is the tallest structure in Texas (excluding radio antennas) south of Houston, the second-tallest observation tower in the United States, and third-tallest in the Western Hemisphere. The second-tallest structure and tallest building in the city is the Marriott Rivercenter. The history of skyscrapers in San Antonio began with the construction of the Tower Life Building (originally the Smith-Young Tower) in 1928, which is often regarded as the first skyscraper in the city. Proposed towers in the central city are Villita Tower a 32-story residential tower, Canopy by Hilton, a 24-story tower on the Riverwalk and the 21-story Thompson Hotels & Residences. In early October 2017, notice of a 900 ft Ferris wheel/observation wheel was given to the FAA for an area south of Downtown San Antonio.

Tallest buildings

This list ranks San Antonio high-rises that stand at least 200 ft tall, based on standard height measurement. This includes spires and architectural details. An equal sign (=) following a rank indicates the same height between two or more buildings. The "Year" column indicates the year in which a building was completed.

Tallest buildings: site prep or under construction

The following are construction projects which will rise at least 200 ft.

Tallest buildings: approved, site plan under review, or proposed

The following are central business district projects which are to rise at least 200 ft. * Table entries with dashes (-) indicate that information regarding building heights or dates of completion has not yet been released.