There are more than 50 completed high-rises in Oklahoma City, most of which stand in the central business district. In the city, 25 buildings stand 200 ft and taller. The tallest building in Oklahoma City, and in Oklahoma, is the 50-story Devon Tower, which rises 844 ft above the central business district. Other notable skyscrapers are Chase Tower and First National Center, which stand as the second and third-tallest buildings in Oklahoma City, respectively. Five of the 10 tallest buildings in Oklahoma are located in Oklahoma City. The history of skyscrapers in Oklahoma City began with the completion of the Colcord Hotel, Oklahoma City's first skyscraper. After oil was discovered in the area, the population of Oklahoma City grew significantly. As a result, the city's skyline expanded, which featured a "race to the top" with the synchronous construction of First National Center and City Place Tower in the central business district. Contemporary skyscrapers began to be built in the north and west sides of Oklahoma City, and later in the downtown area. In 1993, Oklahoma City voters approved the MAPS (Metropolitan Area Projects) program, which featured the construction of several distinct domestic facilities and restorations and expansions of other older ones. It was completed in 2004 and is deemed to be the first program of its kind for a city the size of Oklahoma City. The Devon Tower, which was completed in 2012, has overtaken the Chase Tower as the tallest building in Oklahoma City with a height of 844 ft. It has also become the tallest building in the state of Oklahoma, surpassing the BOK Tower in Tulsa. The 50-story building occupies over 1800000 sqft and had an estimated construction cost of $750 million (USD).

Tallest buildings

This list ranks Oklahoma City skyscrapers that stand at least 61 m tall, based on standard convert measurement; this includes spires and architectural details but does not include antenna masts. The "Year" column indicates the year in which a building was completed.

Under construction buildings

This lists buildings that are under construction in Oklahoma City and are planned to rise at least 100 ft.

Approved and proposed buildings

This lists buildings that are either Proposed or actively Under Design Review with the City of Oklahoma City and are planned to rise at least 100 ft.

Timeline of tallest buildings

This table lists buildings that once held the title of tallest building in Oklahoma City as well as the current titleholder, Devon Energy World Headquarters.