This is a list of supervillains appearing in DC Comics who are or have been enemies of the superhero Superman. Several of Superman's opponents (most notably Darkseid and Brainiac) are or have been foes of the Justice League as well. Unlike most heroes, Superman's adversaries exist in every known capacity; humans, metahumans, androids, sorcerers, empowered animals, other aliens (such as Kryptonians), mythical/supernatural creatures, corrupt doppelgängers of himself (imposters, clones, or parallel universe counterparts), interdimensional beings (Mr. Mxyzpltk, Vyndktvx), and even deities.

Central rogues gallery

In alphabetical order (with issue and date of first appearance):

Foes of lesser renown

In alphabetical order (with issue and date of first appearance):

Group villains

Antiheroes and reformed, semi-reformed, or occasionally reformed supervillains

The following is a list of Superman enemies who have reformed and are more often depicted as allies of alien than enemies.

Allies in conflict

Some characters originally conceived as heroes have come into conflict with Superman.

Enemies created for other media

These are Superman villains created in other media, with no appearances in previous comics.

Villains from comics in other media

A number of villains from the comic books have made an appearance, or appearances, in Superman related live-action media.