This article lists the rulers of Tyrone (Irish: Tír Eoghain) from 1185 to 1616. They are listed from their date of accession to date of death, unless otherwise stated. Prior to this, the ruling dynasty - the Cenél nEógain - were most of the kings of Ailech. During the tenth and eleventh centuries, two main septs within the dynasty emerged; the Meic Lochlainn and the O'Neill. The latter family pushed aside the Meic Lochlainn, and from 1241 onwards the kingdom was ruled exclusively by members of the O'Neill family. For the offshoot Clandeboye O'Neill kingdom, distinct from Tyrone, that was ruled by the descendants of Hugh Boy O'Neill, see List of rulers of Clandeboye.

Kings of Tyrone, 1185—1607

1185–1186 1187–1188 1186–1187 1188–1196 1196–1201 1201–1230 1201 1230 1230–1232 1235–1238 1239–1241 1232–1235 1238–1239 1241–1260 1260–1261 1263–1283 1261–1263 1286–1290 1283–1286 1290–1291 1295–1325 1291–1295 1325–1345 (Contested) 1325–1345 (Contested) 1345–1364 1364–1397 1397–1402 1402–1403 1404–1410 1414–1419 1421–1432 1410–1414 1419–1421 1432–1455 1455–1483 1483–1493 Eleanor FitzGerald || 8 January 1493 1493–1498 1498–1509 1509–1513 1513–1519 Son of Conn Mór mac Éinri O'Neill and Cumach O'Cahan||unknown || 1519 1519–1558 Son of Conn Mór mac Éinri O'Neill and Eleanor FitzGerald ||Alice FitzGerald Sorcha O'Neill || 16 July 1559 1559–1567 Son of Conn O'Neill, 1st Earl of Tyrone and Alice FitzGerald ||Catherine McDonnell Margaret O'Donnell Catherine MacLean || 2 June 1567 Cushendun 1567–1593 Son of Niall Connellagh O'Neill son of Art Oge O'Neill ||Agnes Campbell|| 10 September 1595 1593–1607 Son of Matthew O'Neill, 1st Baron Dungannon (legitimised son of Conn O'Neill, 1st Earl of Tyrone to Alison Kelly) and Siobhan Maguire ||Katherine O'Neill Siobhán O'Donnell Mabel Bagenal Katherine Magennis || 20 July 1616 Rome It could also be argued that Conn Bacach had taken the title Earl of Tyrone in 1542, as part of the process of surrender and regrant, and in the process had waived his title. Whether he could waive it without consulting his clan derbfine is part of this debate. Conn Bacach's grandson Hugh was not proclaimed king at Tullyhogue in 1593, but assumed the title after arranging to pay Turlough Luineach an annuity.