This is a list of defunct department stores of the United States, from small-town one-unit stores to mega-chains, which have disappeared over the past 100 years. Many closed, while others were sold or merged with other department stores.

Department stores merged with Federated and May

Many United States department store chains and local department stores, some with long and proud histories, went out of business or lost their identities between 1986 and 2006 as the result of a complex series of corporate mergers and acquisitions that involved Federated Department Stores and The May Department Stores Company with many stores becoming units of Macy's, Inc. The following is a list of the affected stores, including some local and regional stores that earlier had been absorbed into chains that became part of Federated, May, or Macy's.

Other department stores

Discount Stores

Ames. Bradlees was part of the Stop 'n Shop Companies which was a grocery chain also based in Mass. While there were Bradlees discount stores in the mid Atlantic region, with a buying office on Broadway in the garment center district in NYC; the grocery stores were only in the New England area. Caldor, Service Merchandise, Venture, Woolco, and Zayre were national discount stores that closed due to changes in shopping places and patterns, and/or large debt from mergers and acquisitions.

National and regional

Alabama

Alaska

Arizona

Arkansas

California

Colorado

Connecticut

Delaware

District of Columbia

Florida

Puerto Rico

Georgia

Hawaii

Idaho

Illinois

Indiana

Iowa

Kansas

Kentucky

Louisiana

Maine

Maryland

Massachusetts

Michigan

Minnesota

Mississippi

Missouri

Montana

Nebraska

Nevada

New Hampshire

New Jersey

New Mexico

New York

North Carolina

North Dakota

Ohio

Oklahoma

Oregon

Pennsylvania

Rhode Island

South Carolina

South Dakota

Tennessee

Texas

Utah

Vermont

Virginia

Washington

West Virginia

Wisconsin