The International Symposium on Computer Architecture (ISCA) is an annual academic conference on computer architecture, generally viewed as the top-tier in the field. Association for Computing Machinery's Special Interest Group on Computer Architecture (ACM SIGARCH) and Institute of Electrical and Electronics Engineers Computer Society are technical sponsors. ISCA has participated in the Federated Computing Research Conference in 1993, 1996, 1999, 2003, 2007, 2011, 2015, 2019, and 2023; every year that the conference has been organized. ISCA 2018 hosted the 2017 Turing Award Winners lecture by award winners John L. Hennessy and David A. Patterson. ISCA 2024, which was held in Buenos Aires (Argentina), was the first edition ever to take place in a Latin American country. It featured keynote speakers Mateo Valero, Sridhar Iyengar, and Vivienne Sze. The organization of this edition was led by Prof. Esteban Mocskos (University of Buenos Aires) and Dr. Augusto Vega (IBM T. J. Watson Research Center).

Influential Paper Award

The ISCA Influential Paper Award is presented annually at ISCA by SIGARCH and TCCA. The award is given for the paper with the most impact in the field (in the area of research, development, products, or ideas) from the conference 15 years ago. Prior recipients include: