IARC group 2A agents are substances and exposure circumstances that have been classified as probable carcinogens by the International Agency for Research on Cancer (IARC). This designation is applied when there is limited evidence of carcinogenicity in humans, as well as sufficient evidence of carcinogenicity in experimental animals. In some cases, an agent may be classified in this group when there is inadequate evidence of carcinogenicity in humans along with sufficient evidence of carcinogenicity in experimental animals and strong evidence that the carcinogenesis is mediated by a mechanism that also operates in humans. Exceptionally, an agent may be classified in this group solely on the basis of limited evidence of carcinogenicity in humans. This list is focusing on the hazard linked to the agents. This means that the carcinogenic agents are capable of causing cancer, but this does not take their risk into account, which is the probability of causing a cancer given the level of exposure to this carcinogenic agent. The list is uptodate as of January 2024.

Agents

Substances

Pathogens

Mixtures

Exposure circumstances