Gmina Perlejewo is a rural gmina (administrative district) in Siemiatycze County, Podlaskie Voivodeship, in north-eastern Poland. Its seat is the village of Perlejewo, which lies approximately 26 km north-west of Siemiatycze and 74 km south-west of the regional capital Białystok. The gmina covers an area of 106.32 km2, and as of 2006 its total population is 3,149.

Villages

Gmina Perlejewo contains the villages and settlements of Borzymy, Czarkówka Duża, Czarkówka Mała, Głęboczek, Głody, Granne, Kobyla, Koski Duże, Koski-Wypychy, Kruzy, Leśniki, Leszczka Duża, Leszczka Mała, Miodusy-Dworaki, Miodusy-Inochy, Miodusy-Pokrzywne, Moczydły-Dubiny, Moczydły-Kukiełki, Moczydły-Pszczółki, Nowe Granne, Olszewo, Osnówka, Osnówka-Wyręby, Pełch, Perlejewo, Pieczyski, Poniaty, Stare Moczydły, Twarogi Lackie, Twarogi Ruskie, Twarogi-Mazury, Twarogi-Trąbnica, Twarogi-Wypychy and Wiktorowo.

Neighbouring gminas

Gmina Perlejewo is bordered by the gminas of Ciechanowiec, Drohiczyn, Grodzisk and Jabłonna Lacka.