The House of Giustiniani was a prominent Italian family which originally belonged to Venice, but also established itself in Genoa, and at various times had representatives in Naples, Canary Islands, Corsica and in the islands of the Archipelago, where they had been the last Genoese rulers of the Aegean island of Chios, which had been a family possession for two centuries until 1566. The family claimed descent from Byzantine emperor Justinian I.

In Venice

In the Venetian line the following are most worthy of mention: The Venetian branches of the Giustiniani family are extinct. The family name and arms have been assumed by Baron Girolamo de Massa (1946) and his sons, Sebastiano, Andrea, Nicolò, Pio, Giorgio and Lorenzo, and their descendants, by testamentary disposition of the mother, Elisabetta Giustiniani (Giulio Giustiniani of St. Barnabas's daughter, sister of Maria Giustiniani married Vettor Giusti del Giardino and of Sebastiano Giustiniani, both without descendants).

In Genoa

Of the Genoese branch of the family the most prominent members were the following:

Others

The following are also noteworthy:

Notable properties