Ghassan Shakaa (1943 – 25 Jan 2018) was a Palestinian politician who was the mayor of Nablus in 1994–2004 and in 2012–2015, one of the largest cities in the West Bank. His uncle, Bassam Shaka was another former Nablus mayor. Shakaa was appointed to his position by Yasser Arafat. His brother was assassinated in 2003. Shakaa published an open letter in which he called for the Palestinian National Authority to restore order to his politically divided city. Shakaa died on January 25, 2018 at the age of 74.