George Frederick Whitworth (March 15, 1816 – October 6, 1907 ) was an American Presbyterian missionary, educated at Hanover College in Indiana. Whitworth worked as a minister in the Ohio Valley until 1853, when he and his family moved to the Western frontier. In 1867, he co-founded the Lake Washington Coal Company. He was active in the founding of the first church in Grand Mound, Washington, which he co-pastored with J. W. Goodell (father of pioneer Phoebe Judson). He was the president of the University of Washington from 1866 to 1867 and 1874 to 1876, and was the founder of Whitworth College (now Whitworth University) in 1890.

Grave

He is buried at Lake View Cemetery, Seattle, Washington. His grave is an American Presbyterian and Reformed Historic Site (No. 252) registered by the Presbyterian Historical Society, headquartered in Philadelphia.