The Fort Madison–Keokuk, IA-IL-MO Micropolitan Statistical Area, as defined by the United States Census Bureau, locally known as the "Tri-State" area, was an area consisting of three counties – one in southeast Iowa, one in northeast Missouri, and one in west central Illinois, anchored by the cities of Fort Madison, Iowa and Keokuk, Iowa. As of the 2010 census, the μSA had a population of 62,105. An estimate by the Census Bureau, as of July 1, 2012, placed the population at 61,477, a decrease of 1.01%. When the 2023 definitions were released this area was dissolved with Lee County, Iowa being included as part of the Burlington–Fort Madison, IA–IL Combined Statistical Area.

Counties

Communities

Townships

Clark County, Missouri

Hancock County, Illinois

Lee County, Iowa

Demographics

As of the census of 2000, there were 45,468 people, 18,127 households, and 12,327 families residing within the μSA. The racial makeup of the μSA was 94.99% White, 2.36% African American, 0.25% Native American, 0.34% Asian, 0.05% Pacific Islander, 0.90% from other races, and 1.11% from two or more races. Hispanic or Latino of any race were 2.10% of the population. The median income for a household in the μSA was $32,825, and the median income for a family was $39,464. Males had a median income of $29,783 versus $20,869 for females. The per capita income for the μSA was $17,209.