First Presbyterian Church, also known as the Church of Christ, Scientist, is a historic Presbyterian church located at 111 W. Ash Street in Goldsboro, Wayne County, North Carolina. It was built in 1856, and is a one-story, stuccoed, temple form Greek Revival architecture style church. It features an in antis portico with Tuscan order columns and low pitched roof with a painted wooden cupola. In 1953, the building was sold to the Christian Science Society. It was listed on the National Register of Historic Places in 1979.